MicroRNAs from urinary extracellular vesicles are non-invasive early biomarkers of diabetic nephropathy in type 2 diabetes patients with the 'Asian Indian phenotype'.

@article{Prabu2019MicroRNAsFU,
  title={MicroRNAs from urinary extracellular vesicles are non-invasive early biomarkers of diabetic nephropathy in type 2 diabetes patients with the 'Asian Indian phenotype'.},
  author={P. Prabu and S. Rome and C. Sathishkumar and C. Gastebois and E. Meugnier and V. Mohan and M. Balasubramanyam},
  journal={Diabetes & metabolism},
  year={2019},
  volume={45 3},
  pages={
          276-285
        }
}
  • P. Prabu, S. Rome, +4 authors M. Balasubramanyam
  • Published 2019
  • Medicine
  • Diabetes & metabolism
  • AIMS MicroRNAs (miRNAs) from extracellular vesicles (EVs) have been proposed as promising biomarkers for a number of diseases. In this study, their potential as urine-based biomarkers of diabetic nephropathy (DN) was assessed. METHODS MiRNAs were profiled in urinary EVs from 160 fasting subjects with normal glucose tolerance (NGT) and in T2DM patients with either microalbumininuria (MIC) or macroalbuminuria (MAC). RESULTS A total of 73 miRNAs detected in urinary EVs (NGT) were predicted to… CONTINUE READING
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    References

    SHOWING 1-10 OF 51 REFERENCES
    miRNAs in Urine Extracellular Vesicles as Predictors of Early-Stage Diabetic Nephropathy
    • 57
    • PDF
    Urinary Exosomal MicroRNAs in Incipient Diabetic Nephropathy
    • 181
    • PDF
    Plasma levels of hsa-miR-152-3p are associated with diabetic nephropathy in patients with type 2 diabetes
    • M. Roux, C. Perret, +5 authors S. Hadjadj
    • Medicine
    • Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
    • 2018
    • 12
    • PDF
    Differential microRNA Profiles Predict Diabetic Nephropathy Progression in Taiwan
    • 46
    • PDF
    Increased Circulating miR-21 Levels Are Associated with Kidney Fibrosis
    • 153
    • PDF