MicroRNAs expression changes in acute Streptococcus pneumoniae meningitis

  title={MicroRNAs expression changes in acute Streptococcus pneumoniae meningitis},
  author={Ahmed Galal Omran and Mubareka Jagoo and Muhammed Usman Ashhab and Fang He and Huimin Kong and Jing Peng and Fei Yin},
  journal={Translational Neuroscience},
BackgroundDespite prompt and appropriate care, Streptococcus pneumoniae (S. pneumoniae) meningitis remains a key cause of childhood morbidity and mortality. Recently, several studies suggested the possibility of microRNAs (miRNA) involvement in multiple brain and infectious diseases. This study aimed to investigate the expressional changes of brain-enriched miRNAs (124, 134, 9, and 138), and inflammation-related miRNAs (132, 181a, 221, and 222) in the cerebral cortex of acute S. pneumoniae… CONTINUE READING

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