MicroRNAs coordinately regulate protein complexes

  title={MicroRNAs coordinately regulate protein complexes},
  author={Steffen Sass and Sabine Dietmann and Ulrike C. Burk and Simone Brabletz and Dominik Lutter and Andreas Kowarsch and Klaus F. X. Mayer and Thomas Brabletz and Andreas Ruepp and Fabian J. Theis and Yu Wang},
  booktitle={BMC Systems Biology},
In animals, microRNAs (miRNAs) regulate the protein synthesis of their target messenger RNAs (mRNAs) by either translational repression or deadenylation. miRNAs are frequently found to be co-expressed in different tissues and cell types, while some form polycistronic clusters on genomes. Interactions between targets of co-expressed miRNAs (including miRNA clusters) have not yet been systematically investigated. Here we integrated information from predicted and experimentally verified miRNA… CONTINUE READING
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The impact of microRNAs on protein output

Nature • 2008
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