MicroRNAs as Neuronal Fate Determinants.

  title={MicroRNAs as Neuronal Fate Determinants.},
  author={Malin {\AA}kerblom and Johan Jakobsson},
  journal={The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry},
  volume={20 3},
Since the discovery of short, regulatory microRNAs (miRNA) 20 years ago, the understanding of their impact on gene regulation has dramatically increased. Differentiation of cells requires comprehensive changes in regulatory networks at all levels of gene expression. Posttranscriptional regulation by miRNA leads to rapid modifications in the protein level of large gene networks, and it is therefore not surprising that miRNAs have been found to influence the fate of differentiating cells. Several… CONTINUE READING

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