MicroRNAs and the hallmarks of cancer

@article{Dalmay2006MicroRNAsAT,
  title={MicroRNAs and the hallmarks of cancer},
  author={Tam{\'a}s Dalmay and Dylan R W Edwards},
  journal={Oncogene},
  year={2006},
  volume={25},
  pages={6170-6175}
}
It has become clear that particular microRNAs (miRNAs) function either as tumour suppressors or oncogenes, whose loss or overexpression, respectively, has diagnostic and prognostic significance. In several cases, miRNAs have been shown to affect target genes that are involved in the control of cell proliferation and apoptosis. However, malignant tumours display additional traits beyond the acquisition of enhanced growth potential and decreased cell death. Malignant disease is associated with… CONTINUE READING
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