MicroRNAs and haematology: small molecules, big function.

  title={MicroRNAs and haematology: small molecules, big function.},
  author={Charles Henderson Lawrie},
  journal={British journal of haematology},
  volume={137 6},
MicroRNAs are a recently discovered class of small ( approximately 22nt) endogenously expressed translational-repressor RNAs that play key roles in many cellular pathways and whose aberrant expression appears to be a common feature of malignancy. MicroRNAs are expressed in specific haematological cell types and play important regulatory roles in early haematopoietic differentiation, erythropoiesis, granulocytosis, megakaryocytosis and lymphoid development. Additionally, there is an emerging… CONTINUE READING


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