MicroRNAs and Connexins in Bone: Interaction and Mechanisms of Delivery

@article{Plotkin2017MicroRNAsAC,
  title={MicroRNAs and Connexins in Bone: Interaction and Mechanisms of Delivery},
  author={Lilian I Plotkin and Rafael Pacheco-Costa and Hannah M. Davis},
  journal={Current Molecular Biology Reports},
  year={2017},
  volume={3},
  pages={63-70}
}
Purpose of ReviewTo describe the current knowledge on the cross-talk between connexins and microRNAs (miRs) in bone cells.Recent FindingsConnexins play a crucial role on bone development and maintenance, and disruptions in their abundance or localization can affect how bone perceives and responds to mechanical, hormonal, and pharmacological stimuli. Connexin expression can be modified by miRs, which modulate connexin mRNA and protein levels. Recently, different manners by which miRs and… CONTINUE READING
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