MicroRNAs Involvement in Renal Pathophysiology: A Bird's Eye View

  title={MicroRNAs Involvement in Renal Pathophysiology: A Bird's Eye View},
  author={Pradeep Jaswani and Suraj Prakash and Alok Dhar and Rajendra K. Sharma and Neela Prasad and Shipra Agrawal},
  booktitle={Indian journal of nephrology},
MicroRNAs (miRNAs) are known to suppress gene expression by binding to messenger RNAs and in turn regulate different pathophysiological processes. Transforming growth factor-β, mitogen-activated protein kinase signaling, and Wnt signaling-like major pathways associated with miRNAs are involved with kidney diseases. The discovery of miRNAs has provided new insights into kidney pathologies and may provide effective therapeutic strategies. Research has demonstrated the role of miRNAs in a variety… CONTINUE READING