MicroRNAs (miRNAs) in neurodegenerative diseases.

  title={MicroRNAs (miRNAs) in neurodegenerative diseases.},
  author={Peter T. Nelson and Wang-Xia Wang and Bernard W Rajeev},
  journal={Brain pathology},
  volume={18 1},
Aging-related neurodegenerative diseases (NDs) are the culmination of many different genetic and environmental influences. Prior studies have shown that RNAs are pathologically altered during the inexorable course of some NDs. Recent evidence suggests that microRNAs (miRNAs) may be a contributing factor in neurodegeneration. miRNAs are brain-enriched, small ( approximately 22 nucleotides) non-coding RNAs that participate in mRNA translational regulation. Although discovered in the framework of… CONTINUE READING


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a neuronal perspective

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