MicroRNAs: Processing, Maturation, Target Recognition and Regulatory Functions.

  title={MicroRNAs: Processing, Maturation, Target Recognition and Regulatory Functions.},
  author={Girish C. Shukla and Jagjit Singh and S. Barik},
  journal={Molecular and cellular pharmacology},
  volume={3 3},
The remarkable discovery of small noncoding microRNAs (miRNAs) and their role in posttranscriptional gene regulation have revealed another fine-tuning step in the expression of genetic information. A large number of cellular pathways, which act in organismal development and are important in health and disease, appear to be modulated by miRNAs. At the molecular level, miRNAs restrain the production of proteins by affecting the stability of their target mRNA and/or by down-regulating their… CONTINUE READING

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