MicroRNAs: Crucial multi-tasking components in the complex circuitry of tumor metastasis.

@article{Valastyan2009MicroRNAsCM,
  title={MicroRNAs: Crucial multi-tasking components in the complex circuitry of tumor metastasis.},
  author={Scott J. Valastyan and Robert A Weinberg},
  journal={Cell cycle},
  year={2009},
  volume={8 21},
  pages={
          3506-12
        }
}
Distant metastases are the underlying cause of patient mortality in an overwhelming majority of human carcinomas. Certain microRNAs have recently been found capable of regulating the process of tumor metastasis. In this review, we highlight advances within this rapidly emerging field, endeavor to connect known microRNA pathways with recent conceptual advances in the larger field of metastasis research, and speculate regarding the future utility of microRNAs in the diagnosis and treatment of… CONTINUE READING
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