MicroRNAS in endometrial cancer: recent advances and potential clinical applications

  title={MicroRNAS in endometrial cancer: recent advances and potential clinical applications},
  author={Megumi Yanokura and Kouji Banno and Miho Iida and Haruko Irie and Kiyoko Umene and Kenta Masuda and Yusuke Kobayashi and Eiichiro Tominaga and Daisuke Aoki},
  booktitle={EXCLI journal},
Endometrial cancer is a common malignant gynecological tumor, but there are few biomarkers that are useful for early and accurate diagnosis and few treatments other than surgery. However, use of microRNAs (miRNAs) that induces gene downregulation in cells may permit effective and minimally invasive diagnosis and treatment. In endometrial cancer cells, expression levels of miRNAs including miR-185, miR-210 and miR-423 are upregulated and those of miR-let7e, miR-30c and miR-221 are downregulated… CONTINUE READING
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