MicroRNA133a: a new variable in vascular smooth muscle cell phenotypic switching.

@article{Miano2011MicroRNA133aAN,
  title={MicroRNA133a: a new variable in vascular smooth muscle cell phenotypic switching.},
  author={Joseph M. Miano and Eric M. Small},
  journal={Circulation research},
  year={2011},
  volume={109 8},
  pages={825-7}
}
The human genome is replete with digital information, only 1.2% of which comprises protein-coding sequence. The nonprotein-coding sequence encompasses 1 million regulatory elements controlling gene expression and codes for such genomic processes as recombination, replication, splicing, transposition, and structural integration of the genome with the surrounding nucleoskeleton. Throughout such punctuated sequence information is a vast amount of transcribed nonprotein-coding RNA whose functions… CONTINUE READING
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