MicroRNA turnover: when, how, and why.

  title={MicroRNA turnover: when, how, and why.},
  author={Stefan R{\"u}egger and Helge Gro\sshans},
  journal={Trends in biochemical sciences},
  volume={37 10},
MicroRNAs (miRNAs) are short (∼22 nucleotide) RNAs that are important for the regulation of numerous biological processes. Accordingly, the expression of miRNAs is itself tightly controlled by mechanisms acting at the level of transcription as well as processing of miRNA precursors. Recently, active degradation of mature miRNAs has been identified as… CONTINUE READING