MicroRNA signatures differentiate preserved from reduced ejection fraction heart failure

  title={MicroRNA signatures differentiate preserved from reduced ejection fraction heart failure},
  author={C. Watson and S. Gupta and Eoin O'Connell and S. Thum and N. Glezeva and Jasmin Fendrich and J. Gallagher and M. Ledwidge and L. Grote-Levi and K. McDonald and T. Thum},
  journal={European Journal of Heart Failure},
  pages={405 - 415}
  • C. Watson, S. Gupta, +8 authors T. Thum
  • Published 2015
  • Medicine
  • European Journal of Heart Failure
  • Differentiation of heart failure with reduced (HFrEF) or preserved (HFpEF) ejection fraction independent of echocardiography is challenging in the community. Diagnostic strategies based on monitoring circulating microRNA (miRNA) levels may prove to be of clinical value in the near future. The aim of this study was to identify a novel miRNA signature that could be a useful HF diagnostic tool and provide valuable clinical information on whether a patient has HFrEF or HFpEF. 
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