MicroRNA signature in thyroid fine needle aspiration cytology applied to "atypia of undetermined significance" cases.

@article{Shen2012MicroRNASI,
  title={MicroRNA signature in thyroid fine needle aspiration cytology applied to "atypia of undetermined significance" cases.},
  author={R. Shen and S. Liyanarachchi and W. Li and P. Wakely and M. Saji and Jie Huang and R. Nagy and Tisha Farrell and M. Ringel and A. de la Chapelle and R. Kloos and Huiling He},
  journal={Thyroid : official journal of the American Thyroid Association},
  year={2012},
  volume={22 1},
  pages={
          9-16
        }
}
BACKGROUND MicroRNA (miR) expression signatures are proposed to be able to differentiate thyroid cancer from benign thyroid lesions. We selected eight miRs (miR-146b, -221, -187, -197, -346, -30d, -138, and -302c) to examine the potential use of miRs to supplement diagnostic cytology in cases designated as "atypia of undetermined significance." METHODS miR expression was measured in thyroid fine needle aspiration (FNA) specimens by quantitative polymerase chain reaction. Gene expression… Expand
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