MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations.

@article{Ladeiro2008MicroRNAPI,
  title={MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations.},
  author={Yannick Ladeiro and Gabrielle Couchy and Charles Balabaud and Paulette Bioulac-Sage and Laura Pelletier and Sandra Rebouissou and Jessica Zucman-Rossi},
  journal={Hepatology},
  year={2008},
  volume={47 6},
  pages={1955-63}
}
UNLABELLED Molecular classifications defining new tumor subtypes have been recently refined with genetic and transcriptomic analyses of benign and malignant hepatocellular tumors. Here, we performed microRNA (miRNA) profiling in two series of fully annotated liver tumors to uncover associations between oncogene/tumor suppressor mutations and clinical and pathological features. Expression levels of 250 miRNAs in 46 benign and malignant hepatocellular tumors were compared to those of 4 normal… CONTINUE READING
Highly Influential
This paper has highly influenced a number of papers. REVIEW HIGHLY INFLUENTIAL CITATIONS