MicroRNA miR-30 family regulates non-attachment growth of breast cancer cells

@inproceedings{Ouzounova2012MicroRNAMF,
  title={MicroRNA miR-30 family regulates non-attachment growth of breast cancer cells},
  author={Maria D. Ouzounova and Tri D. Vuong and Pierre-Benoit Ancey and Myl{\`e}ne Ferrand and Geoffroy Durand and Florence Le-Calvez Kelm and Carlo M. Croce and Chantal Matar and Zdenko Herceg and Hector Hernandez-Vargas},
  booktitle={BMC Genomics},
  year={2012}
}
A subset of breast cancer cells displays increased ability to self-renew and reproduce breast cancer heterogeneity. The characterization of these so-called putative breast tumor-initiating cells (BT-ICs) may open the road for novel therapeutic strategies. As microRNAs (miRNAs) control developmental programs in stem cells, BT-ICs may also rely on specific miRNA profiles for their sustained activity. To explore the notion that miRNAs may have a role in sustaining BT-ICs, we performed a… CONTINUE READING
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