MicroRNA let-7d regulates the TLX/microRNA-9 cascade to control neural cell fate and neurogenesis

Abstract

MicroRNAs have important functions in the nervous system through post-transcriptional regulation of neurogenesis genes. Here we show that microRNA let-7d, which has been implicated in cocaine addiction and other neurological disorders, targets the neural stem cell regulator TLX. Overexpression of let-7d in vivo reduced neural stem cell proliferation and… (More)
DOI: 10.1038/srep01329

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