MicroRNA in pancreatic ductal adenocarcinoma and its precursor lesions.

@article{Hernandez2016MicroRNAIP,
  title={MicroRNA in pancreatic ductal adenocarcinoma and its precursor lesions.},
  author={Yasmin G Hernandez and Aimee Lee Lucas},
  journal={World journal of gastrointestinal oncology},
  year={2016},
  volume={8 1},
  pages={18-29}
}
Pancreatic ductal adenocarcinoma (PDAC) is the 4(th) deadliest cancer in the United States, due to its aggressive nature, late detection, and resistance to chemotherapy. The majority of PDAC develops from 3 precursor lesions, pancreatic intraepithelial lesions (PanIN), intraductual papillary mucinous neoplasm (IPMN), and mucinous cystic neoplasm. Early detection and surgical resection can increase PDAC 5-year survival rate from 6% for Stage IV to 50% for Stage I. To date, there are no reliable… CONTINUE READING
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