MicroRNA in pancreatic cancer: pathological, diagnostic and therapeutic implications.

@article{Rachagani2010MicroRNAIP,
  title={MicroRNA in pancreatic cancer: pathological, diagnostic and therapeutic implications.},
  author={Satyanarayana Rachagani and Sushil Kumar and Surinder Batra},
  journal={Cancer letters},
  year={2010},
  volume={292 1},
  pages={8-16}
}
MicroRNAs (miRNAs) are a group of small non-coding RNA molecules of 17-25 nucleotides (nt) in length, predicted to control the activity of about 30% of all protein-coding genes in mammals. Altered expressions of miRNAs are reported in various cancers and may associate with cancer pathogenesis, apoptosis, and cell growth, thereby functioning as either tumor suppressors or oncogenes. Recent reports showed that deregulation of miRNA contribute to tumor development and progression and hence, have… CONTINUE READING