MicroRNA in Glioblastoma: An Overview

  title={MicroRNA in Glioblastoma: An Overview},
  author={Barbara Banelli and Alessandra Forlani and Giorgio Allemanni and A. E. Morabito and Maria Pia Pistillo and Massimo Romani},
  booktitle={International journal of genomics},
Glioblastoma is the most aggressive brain tumor and, even with the current multimodal therapy, is an invariably lethal cancer with a life expectancy that depends on the tumor subtype but, even in the most favorable cases, rarely exceeds 2 years. Epigenetic factors play an important role in gliomagenesis, are strong predictors of outcome, and are important determinants for the resistance to radio- and chemotherapy. The latest addition to the epigenetic machinery is the noncoding RNA (ncRNA… CONTINUE READING
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