MicroRNA in Chronic Rhinosinusitis and Allergic Rhinitis

  title={MicroRNA in Chronic Rhinosinusitis and Allergic Rhinitis},
  author={Xin-hao Zhang and Ya‐Na Zhang and Zheng Liu},
  journal={Current Allergy and Asthma Reports},
Inflammatory upper airway diseases, particularly chronic rhinosinusitis (CRS) and allergic rhinitis (AR), have a high worldwide prevalence. CRS and AR involve sustained and exaggerated inflammation that is associated with marked changes in gene and protein expression under tight regulation. A novel group of gene expression regulators is a class of short single-stranded RNA molecules termed microRNAs (miRNAs). miRNAs can cause gene silencing through degradation of target mRNAs or inhibition of… 

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