MicroRNA expression profiling is a potential diagnostic tool for thyroid cancer.

  title={MicroRNA expression profiling is a potential diagnostic tool for thyroid cancer.},
  author={M. Vriens and Julie Weng and I. -S. Suh and Nhung Huynh and Marlon A. Guerrero and Wen T. Shen and Q. Y. Duh and Orlo Herrick Clark and Electron Kebebew},
  volume={118 13},
BACKGROUND Approximately 30% of fine-needle aspiration (FNA) biopsies of thyroid nodules are indeterminate or nondiagnostic. Recent studies suggest microRNA (miRNA, miR) is differentially expressed in malignant tumors and may have a role in carcinogenesis, including thyroid cancer. The authors therefore tested the hypothesis that miRNA expression analysis would identify putative markers that could distinguish benign from malignant thyroid neoplasms that are often indeterminate on FNA biopsy… CONTINUE READING
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