MicroRNA expression profiling in diabetic GK rat model.

@article{Huang2009MicroRNAEP,
  title={MicroRNA expression profiling in diabetic GK rat model.},
  author={Bing Huang and Wenming Qin and Botao Zhao and Yi Shi and Chengguo Yao and Jin Li and Hua-sheng Xiao and Yan Jin},
  journal={Acta biochimica et biophysica Sinica},
  year={2009},
  volume={41 6},
  pages={472-7}
}
MicroRNAs (miRNAs), which are a newly identified class of small single-stranded non-coding RNAs, regulate their target genes via post-transcriptional pathway. It has been proved that miRNAs play important roles in many biological processes. To better understand miRNA function on type 2 diabetes, we used an oligonucleotide microarray to monitor miRNA expression profiles of Goto-Kakizaki (GK) and Wistar rats' skeletal muscle. It was found that seven miRNAs were downexpressed and two miRNAs were… CONTINUE READING

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