MicroRNA expression profiles classify human cancers

@article{Lu2005MicroRNAEP,
  title={MicroRNA expression profiles classify human cancers},
  author={Jun Lu and Gad Getz and Eric Alexander Miska and Ezequiel Alvarez-Saavedra and Justin Lamb and David Peck and Alejandro Sweet-Cordero and Benjamin L. Ebert and Raymond H. Mak and Adolfo A. Ferrando and James R. Downing and Tyler Jacks and H. Robert Horvitz and Todd R. Golub},
  journal={Nature},
  year={2005},
  volume={435},
  pages={834-838}
}
Recent work has revealed the existence of a class of small non-coding RNA species, known as microRNAs (miRNAs), which have critical functions across various biological processes. Here we use a new, bead-based flow cytometric miRNA expression profiling method to present a systematic expression analysis of 217 mammalian miRNAs from 334 samples, including multiple human cancers. The miRNA profiles are surprisingly informative, reflecting the developmental lineage and differentiation state of the… 
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