MicroRNA expression profiles associated with mutational status and survival in malignant melanoma.

@article{Caramuta2010MicroRNAEP,
  title={MicroRNA expression profiles associated with mutational status and survival in malignant melanoma.},
  author={Stefano Caramuta and Suzanne Egyh{\'a}zi and Monica Rodolfo and Daniela Witten and Johan Hansson and Catharina Larsson and Weng-Onn Lui},
  journal={The Journal of investigative dermatology},
  year={2010},
  volume={130 8},
  pages={2062-70}
}
Malignant cutaneous melanoma is a highly aggressive form of skin cancer. Despite improvements in early melanoma diagnosis, the 5-year survival rate remains low in advanced disease. Therefore, novel biomarkers are urgently needed to devise new means of detection and treatment. In this study, we aimed to improve our understanding of microRNA (miRNA) deregulation in melanoma development and their impact on patient survival. Global miRNA expression profiles of a set of melanoma lymph node… CONTINUE READING

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