MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis.

@article{Bloomston2007MicroRNAEP,
  title={MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis.},
  author={Mark A Bloomston and Wendy L. Frankel and Fabio Petrocca and Stefano Volinia and Hansjuerg Alder and John P. Hagan and Chang-gong Liu and Darshna Bhatt and Cristian Taccioli and Carlo M. Croce},
  journal={JAMA},
  year={2007},
  volume={297 17},
  pages={1901-8}
}
CONTEXT While global microRNA (miRNA) expression patterns of many embryologic, physiologic, and oncogenic processes have been described, description of the role of miRNAs in ductal adenocarcinoma of the pancreas is lacking. OBJECTIVE To define the expression pattern of miRNAs in pancreatic cancer and compare it with those of normal pancreas and chronic pancreatitis. DESIGN AND SETTING Specimens were obtained at a National Cancer Institute-designated comprehensive cancer center from patients… CONTINUE READING
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