MicroRNA expression, survival, and response to interferon in liver cancer.

@article{Ji2009MicroRNAES,
  title={MicroRNA expression, survival, and response to interferon in liver cancer.},
  author={Junfang Ji and Jiong Shi and Anuradha S. Budhu and ZhiPeng Yu and Marshonna Forgues and Stephanie Roessler and Stefan Ambs and Yongmei Chen and Paul S. Meltzer and Carlo M Croce and Lunxiu Qin and Kwan Man and Chung-Mau Lo and Joyce M Lee and Irene Oi-lin Ng and Jia Fa Fan and Zhao-you Tang and Hui-Chuan Sun and Xin Wei Wang},
  journal={The New England journal of medicine},
  year={2009},
  volume={361 15},
  pages={
          1437-47
        }
}
BACKGROUND Hepatocellular carcinoma is a common and aggressive cancer that occurs mainly in men. We examined microRNA expression patterns, survival, and response to interferon alfa in both men and women with the disease. METHODS We analyzed three independent cohorts that included a total of 455 patients with hepatocellular carcinoma who had undergone radical tumor resection between 1999 and 2003. MicroRNA-expression profiling was performed in a cohort of 241 patients with hepatocellular… CONTINUE READING

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