MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer.

Abstract

While altered expression of microRNAs (miRs) in tumors has been well documented, it remains unclear how the miR transcriptome intersects neoplastic progression. By profiling the miR transcriptome we identified miR expression signatures associated with steps in tumorigenesis and the acquisition of hallmark capabilities in a prototypical mouse model of cancer… (More)
DOI: 10.1101/gad.1820109

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