MicroRNA biomarkers of pancreatic injury in a canine model.

@article{Rouse2017MicroRNABO,
  title={MicroRNA biomarkers of pancreatic injury in a canine model.},
  author={Rodney Rouse and Barry A. Rosenzweig and Katie Shea and Alan Knapton and Sharron R Stewart and Lin Xu and Ashok K Chockalingam and Leah Zadrozny and Karol L. Thompson},
  journal={Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie},
  year={2017},
  volume={69 1},
  pages={
          33-43
        }
}
Pancreas-enriched microRNAs have been experimentally investigated in rodents as candidate serum biomarkers of pancreatic injury with several different acute pancreatic injury models. In the present study, temporal and magnitude responses of exocrine pancreas-enriched miR-216a, miR-216b, and miR-217 and endocrine-enriched miR-375 and miR-148a were measured by droplet digital PCR in serum in a caerulein model of pancreatic injury in the dog. All 5 microRNAs followed a similar time course that… CONTINUE READING
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