MicroRNA and vascular remodelling in acute vascular injury and pulmonary vascular remodelling.

@article{McDonald2012MicroRNAAV,
  title={MicroRNA and vascular remodelling in acute vascular injury and pulmonary vascular remodelling.},
  author={Robert A. McDonald and Akiko Hata and Margaret R. Maclean and Nicholas W Morrell and Andrew H. Baker},
  journal={Cardiovascular research},
  year={2012},
  volume={93 4},
  pages={594-604}
}
Vascular remodelling is an integral pathological process central to a number of cardiovascular diseases. The complex interplay between distinct cell populations in the vessel wall following vascular injury leads to inflammation, cellular dysfunction, pro-growth signals in the smooth muscle cell (SMC) compartment, and the acquisition of a synthetic phenotype. Although the signals for vascular remodelling are diverse in different pathological contexts, SMC proliferation and migration are… CONTINUE READING
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