MicroRNA and cancer: Current status and prospective.

  title={MicroRNA and cancer: Current status and prospective.},
  author={Wei Biao Wu and Miao Sun and Gang-Ming Zou and Jianjun Chen},
  journal={International journal of cancer},
  volume={120 5},
Gene expression in normal cells is highly regulated by complex gene regulatory networks. Disruption of these networks may lead to cancer. Recent studies have revealed the existence of an abundant class of small nonprotein-coding regulatory RNAs, known as microRNAs (miRNAs). MiRNAs may regulate diverse biological processes including development, cell proliferation, differentiation and apoptosis, through suppressing the expression of their target genes. Posttranscriptional silencing of target… CONTINUE READING
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