MicroRNA Regulation of Cholesterol Metabolism

@inproceedings{Rotllan2012MicroRNARO,
  title={MicroRNA Regulation of Cholesterol Metabolism},
  author={Noemi Rotllan and Carlos Fern{\'a}ndez-Hernando},
  booktitle={Cholesterol},
  year={2012}
}
Disruption of cellular cholesterol balance results in pathologic processes including atherosclerosis, metabolic syndrome, type II diabetes and Alzheimer's disease. Maintenance of cholesterol homeostasis requires constant metabolic adjustment, achieved partly through the fine regulation of the classical transcription factors (e.g., by SREBP and LXR), but also through members of a class of noncoding RNAs termed miRNAs. Some miRNAs have now been identified to be potent post-transcriptional… CONTINUE READING
Tweets
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
SHOWING 1-10 OF 24 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 77 REFERENCES

MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis

  • S. H. Najafi, F. Kristo, Y. Li
  • Science, vol. 328, no. 5985, pp. 1566–1569, .
  • 2010
Highly Influential
3 Excerpts

Nonalcoholic fatty liver disease is associated with an altered hepatocyte microRNA profile in LDL receptor knockout mice

  • M. Hoekstra, R. J. van der Sluis, J. Kuiper, T.J.C. Van Berkel
  • Journal of Nutritional Biochemistry, vol. 23, no…
  • 2012

Similar Papers

Loading similar papers…