MicroRNA Expression Changes during Interferon-Beta Treatment in the Peripheral Blood of Multiple Sclerosis Patients

@inproceedings{Hecker2013MicroRNAEC,
  title={MicroRNA Expression Changes during Interferon-Beta Treatment in the Peripheral Blood of Multiple Sclerosis Patients},
  author={Michael Hecker and Madhan Thamilarasan and Dirk Koczan and Ina Schroeder and Kristin Flechtner and Sherry Freiesleben and Georg Fuellen and Hans-J{\"u}rgen Thiesen and Uwe K. Zettl},
  booktitle={International journal of molecular sciences},
  year={2013}
}
MicroRNAs (miRNAs) are small non-coding RNA molecules acting as post-transcriptional regulators of gene expression. They are involved in many biological processes, and their dysregulation is implicated in various diseases, including multiple sclerosis (MS). Interferon-beta (IFN-beta) is widely used as a first-line immunomodulatory treatment of MS patients. Here, we present the first longitudinal study on the miRNA expression changes in response to IFN-beta therapy. Peripheral blood mononuclear… CONTINUE READING
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