MicroRNA-98 Suppress Warburg Effect by Targeting HK2 in Colon Cancer Cells

  title={MicroRNA-98 Suppress Warburg Effect by Targeting HK2 in Colon Cancer Cells},
  author={Weimin Zhu and Yijiao Huang and Qi Pan and P. F. Xiang and Nanlan Xie and Hao Yu},
  journal={Digestive Diseases and Sciences},
Warburg effect is a hallmark of cancer cells. Accumulating evidence suggests that microRNAs (miRs) could regulate such metabolic reprograming. Aberrant expression of miR-98 has been observed in many types of cancers. However, its functions and significance in colon cancer remain largely elusive. To investigate miR-98 expression and the biological functions in colon cancer progression. miR-98 expression levels were determined by quantitative RT-PCR in 215 cases of colon cancer samples. miR-98… CONTINUE READING


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