MicroRNA 96 is a post-transcriptional suppressor of anaplastic lymphoma kinase expression.

@article{Vishwamitra2012MicroRNA9I,
  title={MicroRNA 96 is a post-transcriptional suppressor of anaplastic lymphoma kinase expression.},
  author={Deeksha Vishwamitra and Yong Li and Desiree Wilson and Roxsan Manshouri and Choladda V. Curry and Bin P Shi and Xi Tang and Andrea M Sheehan and Ignacio Wistuba and Ping Shi and Hesham M. Amin},
  journal={The American journal of pathology},
  year={2012},
  volume={180 5},
  pages={1772-80}
}
Anaplastic lymphoma kinase (ALK) constitutes a part of the oncogenic fusion proteins nucleophosmin-ALK and echinoderm microtubule-associated protein like 4-ALK, which are aberrantly expressed in a subset of T-cell anaplastic large-cell lymphoma and non-small-cell lung cancer, respectively. The expression of mutated, constitutively active ALK also occurs in a subset of neuroblastoma tumors. ALK is believed to play an important role in promoting tumor survival. Nevertheless, the mechanisms… CONTINUE READING