MicroRNA-95 promotes cell proliferation and targets sorting Nexin 1 in human colorectal carcinoma.

@article{Huang2011MicroRNA95PC,
  title={MicroRNA-95 promotes cell proliferation and targets sorting Nexin 1 in human colorectal carcinoma.},
  author={Zhaohui Huang and Shenglin Huang and Qifeng Wang and Linhui Liang and Shujuan Ni and Lisha Wang and Weiqi Sheng and Xianghuo He and Xiang Du},
  journal={Cancer research},
  year={2011},
  volume={71 7},
  pages={2582-9}
}
MicroRNAs (miRNAs) are strongly implicated in cancer but their specific roles and functions in the major cancers have yet to be fully elucidated. In this study, we defined the oncogenic significance and function of miR-95, which we found to be elevated in colorectal cancer (CRC) tissues by microarray analysis. Evaluation of an expanded CRC cohort revealed that miR-95 expression was up-regulated in nearly half of the tumors examined (42/87) compared with the corresponding noncancerous tissues… CONTINUE READING
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