MicroRNA-93 suppress colorectal cancer development via Wnt/β-catenin pathway downregulating

@article{Tang2014MicroRNA93SC,
  title={MicroRNA-93 suppress colorectal cancer development via Wnt/β-catenin pathway downregulating},
  author={Qingchao Tang and Zhaoxia Zou and Chendan Zou and Qian Zhang and Rui Huang and Xu Guan and Qiang Li and Zhongjing Han and Dayong Wang and Huiyan Wei and Xu Gao and Xishan Wang},
  journal={Tumor Biology},
  year={2014},
  volume={36},
  pages={1701-1710}
}
MicroRNA-93 (miR-93) is involved in several carcinoma progressions. It has been reported that miR-93 acts as a promoter or suppressor in different tumors. However, till now, the role of miR-93 in colon cancer is unclear. Herein, we have found that expression of miR-93 was lower in human colon cancer tissue and colorectal carcinoma cell lines compared with normal colon mucosa. Forced expression of miR-93 in colon cancer cells inhibits colon cancer invasion, migration, and proliferation… CONTINUE READING
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