MicroRNA-92b regulates expression of the oligopeptide transporter PepT1 in intestinal epithelial cells.

@article{Dalmasso2011MicroRNA92bRE,
  title={MicroRNA-92b regulates expression of the oligopeptide transporter PepT1 in intestinal epithelial cells.},
  author={Guillaume Dalmasso and Hang Nguyen and Yutao Yan and Hamed Laroui and Moiz A. Charania and Tracy Sitler Obertone and Shanthi V. Sitaraman and Didier Merlin},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2011},
  volume={300 1},
  pages={G52-9}
}
MicroRNAs (miRNAs), which are noncoding RNAs that posttranscriptionally inhibit expression of target genes, have recently emerged as important regulators of many cellular functions such as cell differentiation. The epithelial di/tripeptide membrane transporter PepT1 is expressed in highly differentiated cells (the villous tip) but not in undifferentiated cells (the crypt) of the small intestine. Here, we investigated the regulation of PepT1 expression by miRNAs and its functional consequences… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 34 references

Immuno-localization of H+/peptide cotransporter in rat digestive tract.

Biochemical and biophysical research communications • 1996
View 5 Excerpts
Highly Influenced

MicroRNAs determine human intestinal epithelial cell fate.

Differentiation; research in biological diversity • 2010

Changes in mRNA expression levels of solute carrier transporters in inflammatory bowel disease patients.

Drug metabolism and disposition: the biological fate of chemicals • 2009
View 2 Excerpts

- 194 is regulated by HNF - 1 alpha during intestinal epithelial cell differentiation

RC Lee, RL Feinbaum, V Ambros
2008

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