MicroRNA-9: functional evolution of a conserved small regulatory RNA.

@article{YuvaAydemir2011MicroRNA9FE,
  title={MicroRNA-9: functional evolution of a conserved small regulatory RNA.},
  author={Yeliz Yuva-Aydemir and Alfred Simkin and Eduardo Gascon and Fen-Biao Gao},
  journal={RNA biology},
  year={2011},
  volume={8 4},
  pages={557-64}
}
The functional significance of microRNA-9 (miR-9) during evolution is evidenced by its conservation at the nucleotide level from flies to humans but not its diverse expression patterns. Recent studies in several model systems reveal that miR-9 can regulate neurogenesis through its actions in neural or non-neural cell lineages. In vertebrates, miR-9 exerts diverse cell-autonomous effects on the proliferation, migration, and differentiation of neural progenitor cells by modulating different mRNA… CONTINUE READING