MicroRNA-650 Was a Prognostic Factor in Human Lung Adenocarcinoma and Confers the Docetaxel Chemoresistance of Lung Adenocarcinoma Cells via Regulating Bcl-2/Bax Expression

@inproceedings{Huang2013MicroRNA650WA,
  title={MicroRNA-650 Was a Prognostic Factor in Human Lung Adenocarcinoma and Confers the Docetaxel Chemoresistance of Lung Adenocarcinoma Cells via Regulating Bcl-2/Bax Expression},
  author={Jia-Yuan Huang and Shi-Yun Cui and Yi-Tian Chen and Hai-zhu Song and Gui-Chun Huang and Bing Feng and Ming Sun and Wei De and Rui Wang and Long-bang Chen},
  booktitle={PloS one},
  year={2013}
}
Increasing evidence shows that dysregulation of microRNAs (miRNAs) is involved in malignant transformation. We investigated the clinical significance of miR-650 and its involvement in chemoresistance to docetaxel. Our results showed that the relative expression level of miR-650 was significantly higher in LAD tissues than in corresponding nontumor tissues and high level of miR-650 expression was found to be significantly associated with high incidence of lymph node metastasis, advanced clinical… CONTINUE READING

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Acquisition of Chemoor Radioresistance and Epithelial to Mesenchymal Transition (EMT) Phenotypes in Docetaxel-Resistant Lung Adenocarcinoma Cells was Linked with Downregulation of Let-7c

  • SY Cui, JY Huang, YT Chen, HZ Song, B Feng
  • Mol Cancer Res: 2013 Apr 5. [Epub ahead of print]
  • 2013
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