MicroRNA-638 inhibits cell proliferation, invasion and regulates cell cycle by targeting tetraspanin 1 in human colorectal carcinoma

@inproceedings{Zhang2014MicroRNA638IC,
  title={MicroRNA-638 inhibits cell proliferation, invasion and regulates cell cycle by targeting tetraspanin 1 in human colorectal carcinoma},
  author={Jiwei Zhang and Bojian Fei and Qifeng Wang and Mingxu Song and Yuan M Yin and Binbin Zhang and Shujuan Ni and Weijie Guo and Zehua Bian and Chao Quan and Zhihui Liu and Yugang Wang and Jian Yu and Xiang Du and Dong Hua and Zhaohui Huang},
  booktitle={Oncotarget},
  year={2014}
}
The expression of miR-638 was found downregulated in colorectal carcinoma (CRC) in our previous study. However, the role of miR-638 in CRC remains unknown. The aim of this study was to determine the function and mechanism of miR-638 in CRC. Here, we verified that miR-638 was frequently downregulated in CRC tissues compared with corresponding noncancerous tissues (NCTs) in an expanded CRC cohort, and survival analysis showed that the downregulation of miR-638 in CRC was associated with poor… CONTINUE READING
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