MicroRNA 628-5p as a Novel Biomarker for Cardiac Allograft Vasculopathy.

  title={MicroRNA 628-5p as a Novel Biomarker for Cardiac Allograft Vasculopathy.},
  author={Anneke Neumann and L Christian Napp and Jan A Kleeberger and Nils Benecke and Angelika Pfanne and Axel Haverich and Thomas Thum and Christoph Bara},
  volume={101 1},
BACKGROUND Cardiac allograft vasculopathy (CAV) remains the leading cause of morbidity and mortality after orthotopic heart transplantation (OHT). Because of its clinically silent progression and lack of symptoms, detection is often difficult and invasive coronary angiography is performed routinely. To date, there are no established noninvasive biomarkers available for prediction of CAV in transplanted patients.MicroRNAs (miRNAs) are highly conserved, small noncoding RNA molecules that… CONTINUE READING
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