MicroRNA-572 expression in multiple sclerosis patients with different patterns of clinical progression

@inproceedings{Mancuso2015MicroRNA572EI,
  title={MicroRNA-572 expression in multiple sclerosis patients with different patterns of clinical progression},
  author={R Garc{\'i}a Mancuso and Ambra Hernis and Simone Agostini and Marco Rovaris and Domenico Caputo and Mario Clerici},
  booktitle={Journal of Translational Medicine},
  year={2015}
}
Demyelination and failure of remyelination are core mechanisms in the pathogenesis of multiple sclerosis (MS); the factor(s) modulating these processes are still mostly unknown. MicroRNA 572 (miR-572) is deregulated in MS and is suggested to targets neural cell adhesion molecule (NCAM), a glycoprotein involved in CNS reparative mechanisms. The aim of this study is to analyze miR-572 in patients with different clinical phenotypes of MS. qPCR quantification of miR-572 isolated from serum was… CONTINUE READING
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