MicroRNA-449a deficiency promotes colon carcinogenesis

Abstract

MicroRNAs have broad roles in tumorigenesis and cell differentiation through regulation of target genes. Notch signaling also controls cell differentiation and tumorigenesis. However, the mechanisms through which Notch mediates microRNA expression are still unclear. In this study, we aimed to identify microRNAs regulated by Notch signaling. Our analysis… (More)
DOI: 10.1038/s41598-017-10500-0

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Cite this paper

@inproceedings{Niki2017MicroRNA449aDP, title={MicroRNA-449a deficiency promotes colon carcinogenesis}, author={Masanori Niki and Kohei Nakajima and Daichi Ishikawa and Jun Nishida and Chieko Ishifune and Shin-ichi Tsukumo and Mitsuo Shimada and Shinji Nagahiro and Yoshinori Mitamura and Koji Yasutomo}, booktitle={Scientific reports}, year={2017} }