MicroRNA-381 represses ID1 and is deregulated in lung adenocarcinoma.

@article{Rothschild2012MicroRNA381RI,
  title={MicroRNA-381 represses ID1 and is deregulated in lung adenocarcinoma.},
  author={Sacha I. Rothschild and Mario P Tschan and Rolf Jaggi and Martin F. Fey and Mathias Gugger and Oliver Gautschi},
  journal={Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer},
  year={2012},
  volume={7 7},
  pages={
          1069-77
        }
}
INTRODUCTION MicroRNAs are small, noncoding RNAs that suppress gene expression by binding to the 3' untranslated region (UTR) and thereby repress translation or decrease messenger RNA stability. Inhibitor of differentiation 1 (ID1) is a putative stem-cell gene involved in invasion and angiogenesis. We previously showed that ID1 is regulated by Src kinases, overexpressed in human lung adenocarcinoma, and targeted by Src-dependent microRNAs. The current study focused on the association between… CONTINUE READING
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  • 2013
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CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 60 REFERENCES

Inhibitor of differentiation-1 as a novel prognostic factor in NSCLC patients with adenocarcinoma histology and its potential contribution to therapy resistance.

  • Clinical cancer research : an official journal of the American Association for Cancer Research
  • 2011
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Lung cancer in 2010: One size does not fit all

  • Nature Reviews Clinical Oncology
  • 2011
VIEW 1 EXCERPT

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