MicroRNA-372 is associated with poor prognosis in colorectal cancer.

  title={MicroRNA-372 is associated with poor prognosis in colorectal cancer.},
  author={Shinya Yamashita and Hirofumi Yamamoto and Koshi Mimori and Naohiro Nishida and Hidekazu Takahashi and Naotsugu Haraguchi and Fumiaki Tanaka and Kohei Shibata and Mitsugu Sekimoto and Hideshi Ishii and Yuichiro Doki and Masaki Mori},
  volume={82 4},
OBJECTIVE MicroRNA-372 (miR-372) is reportedly shown to be an oncogene in human testicular germ cell tumors and gastric cancers, but its expression in colorectal cancer (CRC) is not yet determined. This study investigated the clinical significance of miR-372 expression in CRC. METHODS qRT-PCR was used to evaluate miR-372 in 144 CRC patients, and large tumor suppressor 2 (LATS2) expression was also examined as the likely target gene of miR-372. In vitroassays were performed to evaluate the… CONTINUE READING
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