MicroRNA-365 inhibits growth, invasion and metastasis of malignant melanoma by targeting NRP1 expression.

@article{Bai2015MicroRNA365IG,
  title={MicroRNA-365 inhibits growth, invasion and metastasis of malignant melanoma by targeting NRP1 expression.},
  author={Juanjuan Bai and Zhongling Zhang and Xing Li and Huifan Liu},
  journal={Cancer biomarkers : section A of Disease markers},
  year={2015},
  volume={15 5},
  pages={599-608}
}
OBJECTIVE The role of miR-365 in cancer cells seemed controversial in previous studies. We thereby in this article aimed to define the role of miR-365 in malignant melanoma (MM) pathogenesis. METHODS We detected miR-365 expression in malignant melanoma cell lines and then investigated the effects of miR-365 on the metastasis and malignancy of melanoma cells. The correlation between miR-365 level and NRP1 (neuropilin1) was further investigated in clinical malignant melanoma specimens… CONTINUE READING

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