MicroRNA-34a is induced via p53 during cisplatin nephrotoxicity and contributes to cell survival.

@article{Bhatt2010MicroRNA34aII,
  title={MicroRNA-34a is induced via p53 during cisplatin nephrotoxicity and contributes to cell survival.},
  author={Kirti Bhatt and Li Zhou and Qing-Sheng Mi and Shuang Huang and Jin-Xiong She and Zheng Dong},
  journal={Molecular medicine},
  year={2010},
  volume={16 9-10},
  pages={
          409-16
        }
}
MicroRNAs are small noncoding RNAs that are produced endogenously and have emerged as important regulators in pathophysiological conditions such as development and tumorigenesis. Very little is known about the regulation of microRNAs in renal diseases, including acute kidney injury (AKI). In this study, we examined the regulation of microRNA-34a (miR-34a) in experimental models of cisplatin-induced AKI and nephrotoxicity. By Northern blot and real-time polymerase chain reaction analyses, we… CONTINUE READING

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